Who We Are

The Chicago Center for Functional Annotation (CCFA) is funded as a cooperative agreement research project by the National Institutes of Health (U19 AI107792).  CCFA is directed by Dr. Sean Crosson of the University of Chicago and is composed of scientists from the University of Chicago and the Argonne National Laboratory Biosciences Division.


CCFA research on NIAID priority select agent pathogens, Brucella abortus and Yersinia pestis, is conducted at the University of Chicago Ricketts Lab, a regional biocontainment facility.

The primary research site is the UChicago Howard Taylor Ricketts Regional Biocontainment Lab (HTRL); gene function and data management core facilities are housed within the Argonne Advanced Protein Crystallization Facility (APCF).